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Significantly lower rates of hypoglycemia accompany GLP-1 therapy

Akuta N, Watanabe C, Kawamura Y et al (2017) Effects of a sodium-glucose cotransporter 2 inhibitor in nonalcoholic fatty liver disease complicated by diabetes mellitus: Preliminary prospective study based on serial liver biopsies

To prevent endocytosis, metabolic inhibitors (10 mM NaN 3 , 20 mM 2-deoxyglucose) 9 were added 20 min before labeling completion and maintained throughout the experiment when indicated

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The trial met its primary and secondary endpoints, with patients achieving a mean weight loss of 12.2% at 13 weeks without plateauing, setting the stage for even greater weight loss results in phase 3 development

According to estimates by DAS and confirmed by Gov